Microscopes, applications and theory of Raman, two-photon, coherent Raman and photothermal imaging, adaptive optics, and the open-source tools SpMap and 2D Optics.
First application of adaptive optics in confocal Raman microscopy: a transmissive optofluidic wavefront shaper on the nosepiece corrects sample-induced aberrations, boosting Raman signal up to 3.5x in mouse brain tissue. (ACS Photonics)
Muñoz-Bolaños J.D., Rajaeipour P., Kummer K., Kress M., Ataman Ç., Ritsch-Marte M., Jesacher A. ACS Photonics, doi:10.1021/acsphotonics.4c01432
Read the full article →
A compact dispersive 1064 nm fiber-probe Raman imaging spectrometer that suppresses autofluorescence, discriminates tumor from non-tumor bladder tissue and measures kidney stones. (Applied Sciences)
Read full article →
Optofluidic adaptive optics in multiphoton microscopy: a transmissive, low-loss phase modulator for aberration correction in two-photon imaging. (Biomedical Optics Express)
Read full article →
Open-source Python 3 package for hyperspectral images: preprocessing, baseline correction, clustering and spectral unmixing for Raman, IR and fluorescence data.
Read full article →Hyperspectral analysis for spectroscopists
Load, preprocess and analyse Raman, IR and fluorescence hyperspectral images: smoothing, baseline correction, normalisation, PCA, k-means and hierarchical clustering, and spectral unmixing. Used for the bladder-cancer Raman study.
Optical design & ultrafast optics workbench
Desktop application for designing microscopes and spectrometers: sequential 2D/3D ray tracing with a lens data editor, spot diagrams, ray fans and RMS wavefront; damped-least-squares and global optimisation; gratings and DMDs; ultrafast pulse analysis (spectral phase, GDD, pulse duration); and a dual-pulse nonlinear imaging workbench for SFG, DFG, CARS and SRS. Exports STEP/DXF CAD.
